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Value learning through reinforcement: the basics of dopamine and reinforcement learning

In order to choose advantageously in many circumstances, the values of choice alternatives have to be learned from experience. We provide an introduction to theoretical and experimental work on reinforcement learning, that is, trial-and-error learning to obtain rewards or avoid punishments. We introduce one version, the temporal-difference learning model, and review evidence that its...

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English / 01/01/2014

Valuation for risky and uncertain choices

In this chapter, we describe how risk and ambiguity impact the value of choice options, how this impact can be modelled formally and how it is implemented in the brain. In particular, we give an overview of two distinct ways of how risky choice options can be decomposed – either into outcomes and probabilities as proposed in economics or into statistical moments of the probability...

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English / 01/01/2014

Comparison of functional near-infrared spectroscopy and electrodermal activity in assessing objective versus subjective risk during risky financial decisions.

Risk is an important factor impacting financial decisions. Risk can be processed objectively, e.g. as variance across possible outcomes of a choice option or subjectively, e.g. as value of that variance to a given individual. The aim of the present study was to test the potential of functional near-infrared spectroscopy (fNIRS) in assessing these different ways of processing risk...

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English / 01/01/2014

Experimental methods in cognitive neuroscience

The growth of neuroeconomics as an academic discipline has been inextricably tied to the development of research methods to study brain function and its relationship to behavior. The aim of this chapter is to give an overview of these methods at a cursory level, while at the same time referring the reader to excellent textbooks and primary research articles for more in-depth...

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English / 01/01/2014

The role of learning-related dopamine signals in addiction vulnerability

Psychostimulants such as methylphenidate (MPH) and antidepressants such as fluoxetine (FLX) are widely used in the treatment of various mental disorders or as cognitive enhancers. These medications are often combined, for example, to treat comorbid disorders. There is a considerable body of evidence from animal models indicating that individually these psychotropic medications can...

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English / 01/01/2014

Disentangling neural representations of value and salience in the human brain

A large body of evidence has implicated the posterior parietal and orbitofrontal cortex in the processing of value. However, value correlates perfectly with salience when appetitive stimuli are investigated in isolation. Accordingly, considerable uncertainty has remained about the precise nature of the previously identified signals. In particular, recent evidence suggests that...

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English / 01/01/2014

Activity in dlPFC and its effective connectivity to vmPFC are associated with temporal discounting

There is widespread interest in identifying computational and neurobiological mechanisms that influence the ability to choose long-term benefits over more proximal and readily available rewards in domains such as dietary and economic choice. We present the results of a human fMRI study that examines how neural activity relates to observed individual differences in the discounting of...

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English / 01/01/2014

Fast construction of voxel-level functional connectivity graphs

Background: Graph-based analysis of fMRI data has recently emerged as a promising approach to study brain networks. Based on the assessment of synchronous fMRI activity at separate brain sites, functional connectivity graphs are constructed and analyzed using graph-theoretical concepts. Most previous studies investigated region-level graphs, which are computationally inexpensive, but...

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English / 01/01/2014

Case Report: Practicability of functionally based tractography of the optic radiation during presurgical epilepsy work up

Pre-operative tractography of the optic radiation (OR) has been advised to assess the risk for postoperative visual field deficit (VFD) in certain candidates for resective epilepsy surgery. Diffusion tensor imaging (DTI) tractography relies on a precise anatomical determination of start and target regions of interest (ROIs), such as the lateral geniculate nucleus (LGN) and the...

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English / 01/01/2014

Neural oscillations and synchronization differentially support evidence accumulation in perceptual and value-based decision making

Organisms make two types of decisions on a regular basis. Perceptual decisions are determined by objective states of the world (e.g., melons are bigger than apples), whereas value-based decisions are determined by subjective preferences (e.g., I prefer apples to melons). Theoretical accounts suggest that both types of choice involve neural computations accumulating evidence for the...

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English / 01/01/2014

A game theoretic fundation of competitive quilibria with adverse selection

We construct an extensive form game that captures competitive markets with adverse selection. It allows firms to offer any finite set of contracts, so that cross-subsidization is not ruled out. Moreover, firms can withdraw from the market after initial contract offers have been observed. We show that a subgame perfect equilibrium always exists. In fact, when withdrawal is costless,...

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English / 01/01/2014

Culture, entrepreneurship, and growth

We discuss the two-way link between culture and economic growth. We present a model of endogenous technical change where growth is driven by the innovative activity of entrepreneurs. Entrepreneurship is risky and requires investments that affect the steepness of the lifetime consumption profile. As a consequence, the occupational choice of entrepreneurship hinges on risk tolerance...

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English / 01/01/2014

Return of the Solow Paradox? IT, Productivity, and Employment in US Manufacturing

An increasingly influential "technological-discontinuity" paradigm suggests that IT-induced technological changes are rapidly raising productivity while making workers redundant. This paper explores the evidence for this view among the IT-using US manufacturing industries. There is some limited support for more rapid productivity growth in IT-intensive industries depending...

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English / 01/01/2014

Seeking the roots of entrepreneurship: Insights from behavioral economics†

There is a growing body of evidence that many entrepreneurs seem to enter and persist in entrepreneurship despite earning low risk-adjusted returns. This has lead to attempts to provide explanations—using both standard economic theory and behavioral economics—for why certain individuals may be attracted to such an apparently unprofitable activity. Drawing on research in behavioral...

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English / 01/01/2014

Teens impulsively react rather than retreat from threat

There is a significant inflection in risk taking and criminal behavior during adolescence, but the basis for this increase remains largely unknown. An increased sensitivity to rewards has been suggested to explain these behaviors, yet juvenile offences often occur in emotionally charged situations of negative valence. How behavior is altered by changes in negative emotional processes...

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English / 01/01/2014

The consumption–income ratio, entrepreneurial risk, and the U.S. stock market

The owners of small noncorporate businesses face substantial and largely uninsurable entrepreneurial risk. They are also an important group of stock owners. This paper explores the role of entrepreneurial risk in explaining time variation in expected U.S. stock returns in the period 1952–2010. It proposes an entrepreneurial distress factor that is based on a cointegrating...

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English / 01/01/2014

Rethinking reciprocity

Reciprocal behavioral has been found to play a significant role in many economic domains, including labor supply, tax compliance, voting behavior, and fund-raising. What explains individuals’ tendency to respond to the kindness of others? Existing theories posit internal preferences for the welfare of others, inequality aversion, or utility from repaying others’ kindness. However,...

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English / 01/01/2014

Event-related theta synchronization predicts deficit in facial affect recognition in schizophrenia

Growing evidence suggests that abnormalities in the synchronized oscillatory activity of neurons in schizophrenia may lead to impaired neural activation and temporal coding and thus lead to neurocognitive dysfunctions, such as deficits in facial affect recognition. To gain an insight into the neurobiological processes linked to facial affect recognition, we investigated both induced...

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English / 01/01/2014

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